Addition of proton pump inhibitor to treatment of poorly controlled asthma in children does not improve symptoms

Children without symptoms of gastroesophageal reflux whose asthma was being poorly controlled with anti-inflammatory treatment did not have an improvement in symptoms or lung function with the added treatment of the proton pump inhibitor lansoprazole, compared to patients who received placebo, according to a new study. Use of lansoprazole was associated with increased adverse events.

Adding proton pump inhibitor to treat poorly controlled asthma in children does not improve symptoms

Children without symptoms of gastroesophageal reflux whose asthma was being poorly controlled with anti-inflammatory treatment did not have an improvement in symptoms or lung function with the added treatment of the proton pump inhibitor lansoprazole, compared to patients who received placebo, according to a study in the Jan. 25 issue of JAMA. Use of lansoprazole was associated with increased ...

UVa researcher finds common asthma treatment unbeneficial

“It’s a treatment that’s been used for years in children with asthma, and adults, and it was based on an unproven belief that acid reflux had an important contribution for asthma control."

Asthma Treatment Ineffective, Study Claims

An acid reflux drug used for hard-to-treat asthma doesn't help children with the breathing disease and may cause side effects, a study in 300 children found.

Treatment of silent acid reflux does not improve asthma in children, study finds

Adding the acid reflux drug lansoprazole to a standard inhaled steroid treatment for asthma does not improve asthma control in children who have no symptom of acid reflux, according to a new study. Lansoprazole therapy slightly increased the risk of sore throats and other respiratory problems in children, however.